Study of Cognitive Parameters in Postradiation Period in White Mice

Authors

  • S.L. Kalmakhelidze Ivane Beritashvili Center of Experimental Biomedicine, Laboratory of Neurotoxicology
  • D.P. Museridze Ivane Beritashvili Center of Experimental Biomedicine, Laboratory of Neurotoxicology
  • T.V. Sanikidze Tbilisi State Medical University, Department of Medical Physics and Biophysics
  • M.E. Gogebashvili Ivane Beritashvili Center of Experimental Biomedicine, Laboratory of Radiation Safety Problems
  • D.M. Tophuria Tbilisi State Medical University, Department of Normal Anatomy
  • N.I. Ivanishvili Ivane Beritashvili Center of Experimental Biomedicine, Laboratory of Radiation Safety Problems
  • G.L. Ormotsadze Ivane Beritashvili Center of Experimental Biomedicine, Laboratory of Radiation Safety Problems

DOI:

https://doi.org/10.48614/rrs120213290

Keywords:

Gamma-Irradiation, White Mice, Cognitive Parameters

Abstract

The aim of this study is to identify a dose-and time-dependent correlation betweengammairradiation (5 Gy) inducedcognitive parameters and determine role of irradiation in aging process. Using a laboratory whitemouse model, we showed that ionizing radiation exposures causes spatial memory and behavior changes in different age groups of animals.Study revealed Instant reactions of post-radiation recovery and specificity of long term effects after one year of irradiation.Study of cognitive parameters revealed that gamma irradiation decreases spatial learning process and causes radiation aging, what consolidates the contemporary evidence that radiation can accelerate aging and mortality.

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Published

2021-04-20

How to Cite

Kalmakhelidze, S., Museridze, D., Sanikidze, T., Gogebashvili, M., Tophuria, D., Ivanishvili, N., & Ormotsadze, G. (2021). Study of Cognitive Parameters in Postradiation Period in White Mice. Radiobiology and Radiation Safety, 1(1), 57–62. https://doi.org/10.48614/rrs120213290

Issue

Vol. 1 No. 1 (2021)

Section

Articles