Introduction of Modern Methods of Radiation Genetics into the Medicine in Georgia

Abstract

The article provides an overview of the development of radiation genetics in the Georgian medicine. It considers stages of introduction of genetic methods in the examination of persons exposed to different doses of ionizing radiation under different conditions. The results of chromosomal biodosimetry, introduced since 2000, have been summarized in persons who had received high and low doses as a result of accidents due to contact with abandoned, orphan radiation sources, as well as during professional contacts and in the process of radiation therapy. In addition to the results of chromosomal research, both in total irradiation in accidents as well as during radiotherapy, the importance of using methods for determination of micronuclei level in lymphocytes, buccal and erythroid cells, as well as, using the comet method, DNA damage for the purpose to assess the clinical state of irradiated subjects is being analyzed.